Dynamics of BMP signaling. Note the broad, weak signal early, that refines into a narrow, intense signal by the end.


In our lab, we are interested in identifying how cells in a multicellular organism interpret signals and make decisions, and how the decision-making process adheres to known engineering principles. The ultimate goal is to translate our knowledge to applications such as medicine, stem cell biology, and tissue engineering. Find out more...

Recent News

25 Jul

Hadeel Al Asafen wins image contest!

Graduate student Hadeel Al Asafen has won first place in the NCSU 2018 Envisioning Research contest in the student/postdoc category. Her video can be seen on youtube here. It depicts the dynamics Dorsal gradient when the nuclei are dividing multiple times. Read more about the contest here.

1 Jul

Allison Schloop joins the lab!

We are pleased to announce that a new student from the Genetics Program, Allison Schloop, has joined the lab. Allison earned a bachelor's degree in Biochemistry (and a minor in math) from St. Lawrence University. She will be working on the role of feedforward and feedback loops in the Dorsal gradient system.

11 May

Reeveslab has posted two new manuscripts on bioRχiv

Two recent studies performed in the lab have now been uploaded to the biology preprint server, bioRχiv. In the first study, we have used a panel of wild-caught, naturally-varying fly lines to infer relationships between proteins that act very early in embryo development. Read more here.

In the second study, we have used advanced, quantitative imaging methods to measure how proteins move in the early Drosophila embryo. Understanding protein movement is a major piece in understanding how tissues develop. Read more here.

4 May

Reeveslab welcomes four new members!

This semester, we are pleased to welcome Etika Goyal, Christopher McCallough, Prasad Bandodkar, and Lossie Rooney to the lab. Etika and Christopher are postdocs from Vellore Institute of Technology and University of Illinois at Chicago, respectively. Prasad is most recently from IIT, Delhi (Master's degree), and Lossie recently became a PhD student after studying here at NCSU. See here for more on Reeveslab members.

17 Dec

Reeveslab's fly embryo image featured on BPoD

Biomedical Picture of the Day has featured an image of early fruit fly embryos from our recent work. The image contains two embryos: the one on the left is 1-1.5 hrs younger than the one on the right. During that time span, the transcription factor Dorsal diffuses through the embyro to accumulate on the ventral side. Read more here. Image credit: Sophie Carrell.

13 Dec

NSF highlights our recent work

Our NSF-funded research, which was recently published in Development, has been highlighted on the NSF website. See also our blog post regarding the work.

16 Nov

Our recent publication in the news

Our manuscript recently accepted in Development has been highlighted in a recent news release from NC State. The title of the news article is "Researchers Find Diffusion Plays Unusual Signaling Role in Drosophila Embryos," and can be found here. (It has also been re-posted on various news outlets, such as here and here.)

25 Aug

Dr Reeves receives NIH funding with Drs Rao and Williams

Dr Reeves has received funding from the NIH to begin work on two new projects. In the first, Dr Reeves and Dr Balaji Rao will collaborate to engineer novel sensors to detect RNA and short-lifetime proteins in living tissues. They will use the new technology to study the dynamics of regulatory loops in live tissues and cells.

In the second project, Dr Reeves and Dr Cranos Williams will collaborate to study regulation of signals and decision-making in developing tissues using natural variation. The lab of Dr Trudy Mackay will contrbute fly lines and expertise to the project.

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