News

2017

17 Dec
2017

Reeveslab's fly embryo image featured on BPoD

Biomedical Picture of the Day has featured an image of early fruit fly embryos from our recent work. The image contains two embryos: the one on the left is 1-1.5 hrs younger than the one on the right. During that time span, the transcription factor Dorsal diffuses through the embyro to accumulate on the ventral side. Read more here. Image credit: Sophie Carrell.

13 Dec
2017

NSF highlights our recent work

Our NSF-funded research, which was recently published in Development, has been highlighted on the NSF website. See also our blog post regarding the work.

16 Nov
2017

Our recent publication in the news

Our manuscript recently accepted in Development has been highlighted in a recent news release from NC State. The title of the news article is "Researchers Find Diffusion Plays Unusual Signaling Role in Drosophila Embryos," and can be found here.

06 Nov
2017

ReevesLab is looking for one postdoc

Dr Reeves is looking for one postdoc to join the lab. The project will focus on studying the subtle changes in tissue patterning among a panel of naturally-varying fly lines. These lines have subtle genomic differences, which can be correlated to the changes in gene expression pattern. For more information, see the job posting here. (It has also been re-posted on various news outlets, such as here and here.)

23 Oct
2017

Manuscript accepted in Development!

Our study on the mechanism of Dorsal gradient formation has recently been accepted for publication at Development. The study was led by co-first authors Sophie Carrel and Mike O'Connell, and assisted by current student Tom Jacobsen, and two former undergraduate researchers Amy Pomeroy (Allen) and Stephanie Hayes (Smith).

31 Aug
2017

ReevesLab is looking for two postdocs

Dr Reeves is looking for two postdocs to join the lab on two different projects. The first project will focus on the design of synthetic genetic network motifs in the early fruit fly embryo.

The second project will focus on studying the subtle changes in tissue patterning among a panel of naturally-varying fly lines. These lines have subtle genomic differences, which can be correlated to the changes in gene expression pattern. This job posting will open soon, so check back for details.

UPDATE: the first project has been filled, and the second project is open.

25 Aug
2017

Dr Reeves receives NIH funding with Drs Rao and Williams

Dr Reeves has received funding from the NIH to begin work on two new projects. In the first, Dr Reeves and Dr Balaji Rao will collaborate to engineer novel sensors to detect RNA and short-lifetime proteins in living tissues. They will use the new technology to study the dynamics of regulatory loops in live tissues and cells.

In the second project, Dr Reeves and Dr Cranos Williams will collaborate to study regulation of signals and decision-making in developing tissues using natural variation. The lab of Dr Trudy Mackay will contrbute fly lines and expertise to the project.

11 Aug
2017

Dr Reeves and Dr Hrischuk publish a second review paper

In the paper, Drs Reeves and Hrischuk review published "standard engineering principles" and find that the cell embodies each of these principles (save one). Additionally, they publish a novel list of Chemical Process Control Engineering Principles, and find the cell embodies these as well. The implication is there could be benefits from studying biology from an engineering point of view.

2016

23 Sep
2016

Sophie Carrell earns PhD

Today Sophie has defended her doctoral dissertation! Sophie has published a paper on the microscopy of embryo cross sections, and has another paper on the formation of the Dorsal gradient under revision (see here). She also initiated other projects, including how the relative dosages of Dorsal and Cactus affect patterning and how the Dorsal pathway interacts with the Dpp pathway. Congratulations Dr Carrell!

19 Aug
2016

Ashley Jermusyk publishes paper on synthetic network

Former PhD student and recent graduate Ashley Jermusyk (now a postdoc at the NCI) just had her paper accepted for publication in BMC Systems Biology. She created, analyzed, and refined a synthetic negative feedback loop in the early Drosophila melanogaster embryo. Read more here. Congratulations Ashley!

25 Feb
2016

Ashley Jermusyk earns PhD

Ashley has successfully defended her PhD work! In her time in my lab, she worked on several different projects, including a synthetic negative feedback loop, natural variation of gene expression patterns, and ribozyme-mediated control of gene expression. Congratulations Dr Jermusyk!

29 Jan
2016

Sophie Carrell wins 3rd place at the Schoenborn Symposium

Sophie has won the third place prize at the Schoenborn Symposium for her talk on the formation of the Dorsal gradient in the early Drosophila embryo. The Schoenborn Symposium is an annual research symposium showcasing the body of graduate research in the Department of Chemical and Biomolecular Engineering here at NC State. Congratulations Sophie!

19 Jan
2016

Dr. Reeves and Dr. Curtis Hrischuk publish review paper

Dr. Reeves has published a a review paper in the Computational Biology Journal on the relationship between the fields of systems engineering and systems biology. The crucial observation is that cells constitute embedded computing systems. Check it out!

2015

15 Sep
2015

Ashley Jermusyk publishes chapter on transcription factor networks

Ashley has published a review chapter in the Encyclopedia of Cell Biology. Congratulations Ashley!

20 Aug
2015

Thomas Jacobsen awarded GAANN Fellowship

Tom, a graduate student co-advised by Dr. Beisel and Dr. Reeves, has been awarded a fellowship sponsored by the Graduate Assistance in Areas of National Need (GAANN) program in the area of Biotechnology. Congratulations Tom!

16 Apr
2015

Michael O'Connell publishes paper on the Dorsal gradient

Mike has published a modeling paper in the journal PLoS Computational Biology. His work potentially reveals new roles for Dorsal's inhibitor, Cactus. Congratulations Mike!

2014

10 Oct
2014

Sophie Carrell publishes paper on embryo imaging

Sophie has published a methods protocol in the journal Methods in Molecular Biology. She has refined a method for manual dissection of fixed Drosophila embryos, as well as a method for upright imaging of live embryos. Congratulations Sophie!

16 Apr
2014

Reeves and Sozzani awarded RISF funding

Dr. Reeves and Dr. Rosangela Sozzani (Plant Biology) have been awarded funding through NC State's "Research and Innovation Seed Funding" program. During the next year, they will work on acquiring data on distribution and mobility of signaling molecules in the early Drosophila embryo.

11 Apr
2014

Dr. Reeves and Dr. Beisel awarded NSF funding

Dr. Reeves and colleague Dr. Chase Beisel (also in CBE) receive NSF funding to build and tune synthetic circuits in early Drosophila embryos. Read more here.

2013

22 Jul
2013

Michael O'Connell awarded GAANN Fellowship

Mike O'Connell, a graduate student in the Reeves lab, has been awarded a fellowship sponsored by the Graduate Assistance in Areas of National Need (GAANN) program in the area of Scientific Computing. Congratulations Mike!

19 May
2013

Reeves and Deiters awarded RISF funding

Dr. Reeves and Dr. Alexander Deiters (Chemistry) have been awarded funding through NC State's "Research and Innovation Seed Funding" program. During the next year, they will work on acquiring data on regulation of gene expression in the early Drosophila embryo.

18 Mar
2013

Dr Reeves receives NSF CAREER Award

Dr Reeves has been selected to receive the Faculty Early Career Development (CAREER) Award from the National Science Foundation. From the NSF webpage: This is one of "the National Science Foundation's most prestigious awards in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of education and research within the context of the mission of their organizations. Such activities should build a firm foundation for a lifetime of leadership in integrating education and research." Read more here.

Prior to 2013

7 Jun
2012

Dr Reeves' fly embryo image featured on BPoD

Biomedical Picture of the Day has featured an image of an early fruit fly embryo taken by Dr Reeves. This cross section of a 2.5 hr old embryo reveals the expression of five different genes in a spatial pattern. Read more here.

1 Aug
2011

Dr Reeves selected as NCSU nominee for Pew Award

The Pew Scholars program grants 4-year awards to young professors in the biomedical sciences. Each school that participates in the competition can nominate one individual. In this round of competition, 22 Pew Scholars will be named.

16 Aug
2010

Job posting for undergraduate research

I am currently looking for an undergraduate researcher to help set up my lab and continue working through the Spring 2011 and perhaps into the next year.

9 Jan
2009

Start date for Dr Reeves changed to August 2010

I spoke with the department and together we decided to push my start date back to August of 2010. I will then be recruiting students and/or postdocs to begin that fall semester.




A gradient of nuclear concentration of the transcription factor Dorsal (upper) induces gene expression fates (lower) in the early Drosophila embryo. Images are cross sections. Taken in the Stathopoulos lab.